A REVIEW OF VIRUS HOST FACTOR DISCOVERY USING CRISPR SCREENING

A review of virus host factor discovery using CRISPR screening

ABSTRACT The emergence of genome-scale forward genetic screening techniques, such as Haploid Genetic screen and clustered regularly interspaced short palindromic repeats (CRISPR) knockout screen has opened new horizons in our understanding of virus infection biology.CRISPR screening has become a popular tool for the discovery of novel host factors

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Decreased Wait Time and Increased Satisfaction With Bedside Pancreatic Enzyme Dosing for the Inpatient Adolescent With Cystic Fibrosis: A Quality Improvement Project Comparing Enzyme Self-Administration to Nurse Administration

For children with cystic fibrosis (CF), enzymes are essential with meals to absorb nutrients and ensure adequate growth.When hospitalized, CF patients typically rely on nurse-administered medications.Recently, a pediatric hospital unit began allowing adolescents with CF enzymes at the bedside.Postimplementation, a satisfaction questionnaire was MYR

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Investigating commercial and convenience services installed in intermodal passenger terminals located in mid-sized European cities

The concept of intermodality has gained key importance in the sustainable mobility strategy of the European Union.In the past two decades, different types of intermodal passenger terminals (IPTs) have been built in many European cities.These facilities provide possibility for passengers to change transportation mode or route in a short time and con

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Consequences of lower food intake on the digestive enzymes activities, the energy reserves and the reproductive outcome in Gammarus fossarum.

Digestive enzyme activity is often used as a sensitive response to environmental pollution.However, only little is known Throw about the negative effects of stress on digestive capacities and their consequences on energy reserves and reproduction, although these parameters are important for the maintenance of populations.To highlight if changes in

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Binary Black Hole Spins: Model Selection with GWTC-3

The origin of the spins of stellar-mass black holes is still controversial, and angular momentum transport inside massive stars is one of the main sources of uncertainty.Here, we apply hierarchical Bayesian inference to derive constraints on spin models Zodiac T3 Parts from the 59 most confident binary black hole merger events in the third gravitat

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